Cameron Coates, Graduate student
In 2006 Cameron joined the Gerwick lab as a staff research associate and managed the labs cyanobacterial cultures, field expeditions, and extraction lab. In 2008 Cameron began a PhD program in the Marine Biology Curricular Group and began his thesis research on cyanobcterial hydrocarbon biosynthesis.
Areas of expertise include molecular biology, analytical chemistry, microbiology, marine biology, marine chemistry, biofuels. PhD Thesis: Investigations Of The Structural Variability, Evolutionary History And Biosynthetic Mechanisms Of Cyanobacterial Hydrocarbons. Through an investigation of the structural diversity of hydrocarbon composition from a variety of cyanobacteria my research has revealed novel metabolic steps and parallel pathways. I am investigating the use of these unique enzymatic traits to genetically engineer microbes with enhanced capacity for biofuel production.
Coates RC, Podell S, Korobeynikov A, Lapidus A, Pevzner P, Sherman D, Allen EE, Gerwick L, Gerwick WH (2013) Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways. PLoS One. DOI: 10.137/journal.pone.0085140
Coates RC, Trentacoste E, Gerwick WH (2013) Bioactive and Novel Chemicals from Microalgae. In: Handbook for Microalgal Culture 2 Ed. Eds. Richmond A, Hu Q. Wiley-Blackwell. DOI: 10.1002/9781118567166.ch26
Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu W, Gerwick L, Dorrestein P, Pevzner P, Lasken R, Gerwick W (2011) Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage. PLoS One. 6(4): e18565
Sellheim K, Stachowicz JJ, Coates RC (2010) Effects of a nonnative habitat-forming species on mobile and sessile epifaunal communities. Mar. Ecol. Prog. Ser. 398: 69-80.
Engene N, Coates RC, Gerwick WH (2010) 16S rRNA gene heterogeneity in the filamentous marine cyanobacterial genus Lyngbya. J.Phycol. 46(3): 591-601.
Gerwick WH, Coates RC, Engene N, Gerwick L, Grindberg RV, Jones AC, Sorrels CM (2008) Giant marine cyanobacteria produce exciting potential pharmaceuticals. Microbe 3(6): 277-284.
Gerwick W, Byrum T, Carland T, Coates RC, Engene N, Esquenazi E, Gerwick L, Grindberg R, Johnson M, Jones A, Malloy K, Nunnery J, Pereira A, Soria I, Sorrels C, Taniguchi M, Tidgewell K, Villa F, Vining O, Dorrestein P, Gu L, Sherman DH (2008) Integrating Chemical and Biochemical Approaches to Natural Products Drug Discovery from Marine Cyanobacteria. Proceedings from the New Developments in Drug Discovery on Natural Products and Traditional Medicines NIPER, India 33-43.
Esquenazi E, Coates C, Simmons L, Gonzalez D, Gerwick WH, Dorrestein PC. (2008) Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. Mol Biosyst. (6): 562-570.
Simmons TL, Coates RC, Clark BR, Engene N, Gonzalez D, Esquenazi E, Dorrestein PC, Gerwick W. H. (2008) Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages. PNAS.105(12): 4587-4594.