Center for Marine Biotechnology and Biomedicine
Scripps Institution of Oceanography
University of California San Diego
La Jolla, CA 92093-0212
Lena Gerwick is an associate professor, research in the Marine Biology program and the Center for Marine Biotechnology and Biomedicine. Her research interests involve the evolution and functional aspects of innate immunity and its role in inflammation. Since 1994 she has been researching the inflammatory response in rainbow trout with the focus being the transcriptional response in the liver and the subsequent secretion of many of these proteins to the blood stream. As a result, many of the inflammatory response proteins (acute phase proteins) have been sequenced and for some the expression pattern has been mapped. To further be able to CONTACT some of the functional aspects of some of these innate immune molecules. Furthermore, she is developing tools that can be used for screening of marine natural products as a source of potential new drugs using several innovative assays that measure anti-inflammatory properties. In addition, several members of Lena’s laboratory are actively using modern techniques to determine mechanism of action and specific protein targets of selected natural products, in particular, marine natural products showing anti-inflammatory activity.